MicroRNA-146a rs2910164 is associated with severe preeclampsia in Black South African women on HAART
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چکیده
منابع مشابه
RS2910164 polymorphism in the microrna-146a is associated with risk for type 1 diabetes mellitus
Background Type 1 diabetes mellitus (T1D) is characterized by severe autoimmune destruction of pancreatic beta-cells, which renders subjects insulin-dependent for life. The triggering of autoimmunity against beta-cells is probably caused by a combination of environmental and genetic risk factors. Even though much is known about the genetic of T1D, more information is needed to completely unrave...
متن کاملAssociation of MicroRNA-146a rs2910164 Gene Polymorphism with Metabolic Syndrome.
Alteration in microRNA-146a (miRNA-146a) expression is an important event in the pathogenesis of many human diseases. MiRNA-146a rs2910164 is a functional polymorphism that showed association with several diseases. Metabolic syndrome is an aggregation of multiple risk factors including impaired glucose tolerance, increased highdensity lipoprotein, abdominal obesity, and high blood pressure. The...
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Results of published studies on the association between the miR-146a rs2910164 polymorphism and the risk of hepatocellular carcinoma (HCC) were inclusive. We performed a meta-analysis. A literature research was conducted using PubMed, Cochrane Library, Ovid, Embase, Wanfang and China National Knowledge Infrastructure (CNKI) databases, to identify studies. Statistical analyses were conducted in ...
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Mycobacterium leprae infects macrophages and Schwann cells inducing a gene expression program to facilitate its replication and progression to disease. MicroRNAs (miRNAs) are key regulators of gene expression and could be involved during the infection. To address the genetic influence of miRNAs in leprosy, we enrolled 1,098 individuals and conducted a case-control analysis in order to study fou...
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From 1990 to 2013, there was an 81% increase in deaths from cardiovascular disease (CVD) in sub-Saharan Africa (SSA), with more women dying from CVD than men.1 Obesity, hypertension, dysglycemia and dyslipidaemia are individual as well as inter-related risk factors for CVD. When these risk factors are clustered together, they are known as the metabolic syndrome (MetS).2 MetS has clinical utilit...
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ژورنال
عنوان ژورنال: BMC Genetics
سال: 2017
ISSN: 1471-2156
DOI: 10.1186/s12863-016-0469-z